CD158e1 Antibody [DX9] (PE)
| Code | Size | Price |
|---|
| PSI-99-609-100tests | 100tests | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [DX9]
Regulatory Status: RUO
Target Species:
- Baboon
- Human
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
NKB1, p70, KIR, 3DL1, KIR3DL1, KIR3D, NKAT3
Application Note:
CD158e1 Antibody [DX9] for use in flow cytometry assays.
Background:
CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig)-like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
Lot specific
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human NK clone VL186-1 (CD3-, CD16+, CD56+)
NCBI Gene ID #:
3811
NCBI Official Name:
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
NCBI Official Symbol:
KIR3DL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P43629
Research Area:
Immunology
SPECIFICITY:
CD158e1
Swissprot #:
P43629
User NOte:
Optimal dilutions for each application to be determined by the researcher.