CD19 Antibody [6D5]

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ProSci
Product Code: PSI-98-657
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-98-657-0.5mg0.5mg£560.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [6D5]
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry (IHC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD19-UNLB (Cat. No. 98-657) and Rat Anti-Mouse CD3-FITC followed by Mouse Anti-Rat IgG2a-PE .
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BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD19-UNLB (Cat. No. 98-657) and Rat Anti-Mouse CD3-FITC followed by Mouse Anti-Rat IgG2a-PE .

Documents

Further Information

Additional Names:
B4, Leu-12
Application Note:
CD19 Antibody [6D5] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and separation assays.
Background:
CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse CD19-expressing K562 human erythroleukemia cells
NCBI Gene ID #:
12478
NCBI Official Name:
CD19 antigen
NCBI Official Symbol:
Cd19
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P25918
Research Area:
Immunology
SPECIFICITY:
CD19
Swissprot #:
P25918
User NOte:
Optimal dilutions for each application to be determined by the researcher.