CD19 Antibody [6D5]
| Code | Size | Price |
|---|
| PSI-98-663-0.5mg | 0.5mg | £642.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [6D5]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunocytochemistry (ICC)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at -20˚C
Documents
Further Information
Additional Names:
B4, Leu-12
Application Note:
CD19 Antibody [6D5] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and separation assays.
Background:
CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3.
Buffer:
Supplied in PBS
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse CD19-expressing K562 human erythroleukemia cells
NCBI Gene ID #:
12478
NCBI Official Name:
CD19 antigen
NCBI Official Symbol:
Cd19
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P25918
Research Area:
Immunology
SPECIFICITY:
CD19
Swissprot #:
P25918
User NOte:
Optimal dilutions for each application to be determined by the researcher.