CD24 Antibody [30-F1] (PE-Cy5)
| Code | Size | Price |
|---|
| PSI-98-984-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2c
Antibody Clonality: Monoclonal
Antibody Clone: [30-F1]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Heat stable antigen, HSA
Application Note:
CD24 Antibody [30-F1] for use in flow cytometry assays.
Background:
CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE-Cy5
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse thymus or spleen
NCBI Gene ID #:
12484
NCBI Official Name:
CD24a antigen
NCBI Official Symbol:
Cd24a
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P24807
Research Area:
Immunology
SPECIFICITY:
CD24
Swissprot #:
P24807
User NOte:
Optimal dilutions for each application to be determined by the researcher.