CD30 Antibody [mCD30.1]
| Code | Size | Price |
|---|
| PSI-98-727-0.5mg | 0.5mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: [mCD30.1]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Ki-1, Ber-H2
Application Note:
CD30 Antibody [mCD30.1] for use in flow cytometry, costimulation, stimulation, and blocking assays.
Background:
CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. Murine CD30 is expressed predominantly in the thymus and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-gamma production. While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse CD30-mouse IgG1 fusion protein
NCBI Gene ID #:
21941
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 8
NCBI Official Symbol:
Tnfrsf8
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q60846
Research Area:
Apoptosis
SPECIFICITY:
CD30
Swissprot #:
Q60846
User NOte:
Optimal dilutions for each application to be determined by the researcher.