CD33 Antibody [WM53]
| Code | Size | Price |
|---|
| PSI-99-504-0.1mg | 0.1mg | £373.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [WM53]
Regulatory Status: RUO
Target Species: Human
Applications:
- Blocking
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
gp67, p67, Siglec-3
Application Note:
CD33 Antibody [WM53] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.
Background:
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
945
NCBI Official Name:
CD33 molecule
NCBI Official Symbol:
CD33
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P20138
Research Area:
Immunology,Stem Cell
SPECIFICITY:
CD33
Swissprot #:
P20138
User NOte:
Optimal dilutions for each application to be determined by the researcher.