CD3e Antibody [C363.29B]
| Code | Size | Price |
|---|
| PSI-98-575-0.5mg | 0.5mg | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: [C363.29B]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
CD3 epsilon
Application Note:
CD3e Antibody [C363.29B] for use in flow cytometry, immunohistochemistry, immunoprecipitation, depletion, CMCD, and activation assays.
Background:
CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and na?ve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IL-4 producing Th2 cell lines including D10
NCBI Gene ID #:
12501
NCBI Official Name:
CD3 antigen, epsilon polypeptide
NCBI Official Symbol:
Cd3e
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P22646
Research Area:
Immunology
SPECIFICITY:
CD3epsilon
Swissprot #:
P22646
User NOte:
Optimal dilutions for each application to be determined by the researcher.