CD3e Antibody [C363.29B] (FITC)

ProSci
Product Code: PSI-98-576
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-98-576-0.5mg0.5mg£560.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: [C363.29B]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

1 / 2
C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse CD3-FITC (Cat. No. 98-576) and Rat Anti-Mouse CD19-PE .
2 / 2
Frozen mouse splenic section was stained Rat Anti-Mouse CD3?-FITC (Cat. No. 98-576). Image from Ji F, Liu Z, Cao J, Li N, Liu Z, Zuo J, et al. B cell response is required for granuloma formation in the early infection of Schistosoma japonicum. PLoS One. 2008;3(3):e1724. Figure 5(a)

C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse CD3-FITC (Cat. No. 98-576) and Rat Anti-Mouse CD19-PE .
Frozen mouse splenic section was stained Rat Anti-Mouse CD3?-FITC (Cat. No. 98-576). Image from Ji F, Liu Z, Cao J, Li N, Liu Z, Zuo J, et al. B cell response is required for granuloma formation in the early infection of Schistosoma japonicum. PLoS One. 2008;3(3):e1724. Figure 5(a)

Further Information

Additional Names:
CD3 epsilon
Application Note:
CD3e Antibody [C363.29B] for use in flow cytometry and immunohistochemistry assays.
Background:
CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and na?ve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IL-4 producing Th2 cell lines including D10
NCBI Gene ID #:
12501
NCBI Official Name:
CD3 antigen, epsilon polypeptide
NCBI Official Symbol:
Cd3e
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P22646
Research Area:
Immunology
SPECIFICITY:
CD3epsilon
Swissprot #:
P22646
User NOte:
Optimal dilutions for each application to be determined by the researcher.