CD3e Antibody [145-2C11] (APC)
| Code | Size | Price |
|---|
| PSI-98-562-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: [145-2C11]
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
CD3 epsilon
Application Note:
CD3e Antibody [145-2C11] for use in flow cytometry assays.
Background:
CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and na?ve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL?s. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone BM10-37
NCBI Gene ID #:
12501
NCBI Official Name:
CD3 antigen, epsilon polypeptide
NCBI Official Symbol:
Cd3e
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P22646
Research Area:
Immunology
SPECIFICITY:
CD3epsilon
Swissprot #:
P22646
User NOte:
Optimal dilutions for each application to be determined by the researcher.