CD43 Antibody [DF-T1] (PE-Cy5)
| Code | Size | Price |
|---|
| PSI-99-528-100tests | 100tests | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [DF-T1]
Regulatory Status: RUO
Target Species: Human
Applications:
- Blocking
- Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
gpL115, leukocyte sialoglycoprotein
Application Note:
CD43 Antibody [DF-T1] for use in flow cytometry assays.
Background:
CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells, and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets, and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions including T cell killing, and by increasing the threshold for T cell activation.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
Lot specific
Conjugate:
PE-Cy5
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
KG-1 cells
NCBI Gene ID #:
6693
NCBI Official Name:
sialophorin
NCBI Official Symbol:
SPN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P16150
Research Area:
Immunology
SPECIFICITY:
CD43
Swissprot #:
P16150
User NOte:
Optimal dilutions for each application to be determined by the researcher.