CD44 Antibody [KM201]

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ProSci
Product Code: PSI-98-537
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-98-537-0.5mg0.5mg£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [KM201]
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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BALB/c mouse bone marrow cells were stained with Rat Anti-Mouse CD44-UNLB (Cat. No. 98-537) followed by Mouse Anti-Rat IgG1-FITC .
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BALB/c mouse bone marrow cells were stained with Rat Anti-Mouse CD44-UNLB (Cat. No. 98-537) followed by Mouse Anti-Rat IgG1-FITC .

Documents

Further Information

Additional Names:
Pgp-1, H-CAM, HUTCH-1, ECMR-III
Application Note:
CD44 Antibody [KM201] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, blocking, and adhesion assays.
Background:
CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
(C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2
NCBI Gene ID #:
12505
NCBI Official Name:
CD44 antigen
NCBI Official Symbol:
Cd44
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P15379
Research Area:
Cancer,Immunology
SPECIFICITY:
CD44
Swissprot #:
P15379
User NOte:
Optimal dilutions for each application to be determined by the researcher.