CD44 Antibody [F10-44-2]
| Code | Size | Price |
|---|
| PSI-99-374-0.1mg | 0.1mg | £373.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [F10-44-2]
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Pgp-1, H-CAM, ECMR-III, HUTCH-1
Application Note:
CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, CMCD, cytotoxicity, depletion, adhesion, activation, purification, and blocking assays.
Background:
CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Purified human T cells
NCBI Gene ID #:
960
NCBI Official Name:
CD44 molecule (Indian blood group)
NCBI Official Symbol:
CD44
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P16070
Research Area:
Signal Transduction,Signal Transduction
SPECIFICITY:
CD44
Swissprot #:
P16070
User NOte:
Optimal dilutions for each application to be determined by the researcher.