CD45R Antibody [RA3-6B2]
| Code | Size | Price |
|---|
| PSI-98-785-0.5mg | 0.5mg | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [RA3-6B2]
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
B220, Ly-5, Lyt-4, Ptprc, Receptor-type tyrosine-protein phosphatase C
Application Note:
CD45R Antibody [RA3-6B2] for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, and blocking assays.
Background:
CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Abelson murine leukemia virus-induced pre-B cell lymphoma
NCBI Gene ID #:
19264
NCBI Official Name:
protein tyrosine phosphatase, receptor type, C
NCBI Official Symbol:
Ptprc
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P06800
Research Area:
Immunology
SPECIFICITY:
CD45R
Swissprot #:
P06800
User NOte:
Optimal dilutions for each application to be determined by the researcher.