CD49b Antibody [HAS-4] (FITC)

ProSci
Product Code: PSI-99-383
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-99-383-100tests100tests£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [HAS-4]
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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Human peripheral blood platelets were stained with Mouse Anti-Human CD49b-FITC (Cat. No. 99-383).

Human peripheral blood platelets were stained with Mouse Anti-Human CD49b-FITC (Cat. No. 99-383).

Further Information

Additional Names:
Integrin alpha2, VLA-2alpha, very late antigen-2
Application Note:
CD49b Antibody [HAS-4] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Background:
CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha2 chain. CD49b associates noncovalently with CD29, the integrin beta1 subunit, to form the heterodimer integrin alpha2beta1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts, and long-term cultured T cells. CD49b/CD29 mediates the Mg++-dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during wound healing.
Buffer:
Supplied in PBS/NaN3
Concentration:
Lot specific
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human keratinocytes
NCBI Gene ID #:
3673
NCBI Official Name:
Integrin alpha-2
NCBI Official Symbol:
ITGA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P17301
Research Area:
Cancer,Immunology,Obesity,Signal Transduction
SPECIFICITY:
CD49b
Swissprot #:
P17301
User NOte:
Optimal dilutions for each application to be determined by the researcher.