CD5 Antibody [53-7.3] (FITC)

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ProSci
Product Code: PSI-98-609
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-98-609-0.5mg0.5mg£560.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [53-7.3]
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD5-FITC (Cat. No. 98-609) and Rat Anti-Mouse CD19-PE .
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BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD5-FITC (Cat. No. 98-609) and Rat Anti-Mouse CD19-PE .

Documents

Further Information

Additional Names:
Lyt-1, Ly-1, Lymphocyte antigen 1, Ly-12, Ly-A, T1, Tp67
Application Note:
CD5 Antibody [53-7.3] for use in flow cytometry and immunohistochemistry assays.
Background:
CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Spleen cells or thymocyte membranes
NCBI Gene ID #:
12507
NCBI Official Name:
CD5 antigen
NCBI Official Symbol:
Cd5
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P13379
Research Area:
Cancer,Immunology,Signal Transduction
SPECIFICITY:
CD5
Swissprot #:
P13379
User NOte:
Optimal dilutions for each application to be determined by the researcher.