CD51 Antibody [13C2] (PE)
| Code | Size | Price |
|---|
| PSI-99-552-100tests | 100tests | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [13C2]
Regulatory Status: RUO
Target Species:
- Bovine (Cattle)
- Human
- Rabbit
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Integrin alphaV, vitronectin receptor, VNR-alpha chain
Application Note:
CD51 Antibody [13C2] for use in flow cytometry assays.
Background:
CD51 represents the integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
Lot specific
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Cell suspension containing osteoclasts from osteoclastomas
NCBI Gene ID #:
3685
NCBI Official Name:
integrin, alpha V
NCBI Official Symbol:
ITGAV
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P06756
Research Area:
Other
SPECIFICITY:
CD51
Swissprot #:
P06756
User NOte:
Optimal dilutions for each application to be determined by the researcher.