CD69 Antibody [H1.2F3] (PE-Cy7)
| Code | Size | Price |
|---|
| PSI-98-834-0.1mg | 0.1mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: [H1.2F3]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
VEA, very early activation antigen, AIM, EA1, MLR3, gp34/28, Leu-23
Application Note:
CD69 Antibody [H1.2F3] for use in flow cytometry assays.
Background:
CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly upregulated upon activation of T, B and NK cells, and neutrophils. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. The monoclonal antibody H1.2F3 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE-Cy7
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse dendritic epidermal cell line Y245
NCBI Gene ID #:
12515
NCBI Official Name:
CD69 antigen
NCBI Official Symbol:
Cd69
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P37217
Research Area:
Immunology
SPECIFICITY:
CD69
Swissprot #:
P37217
User NOte:
Optimal dilutions for each application to be determined by the researcher.