CD81 Antibody [2F7] (FITC)
| Code | Size | Price |
|---|
| PSI-98-991-0.5mg | 0.5mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: [2F7]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
TAPA-1
Application Note:
CD81 Antibody [2F7] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Background:
CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gammadelta+ T cells to more mature T cells with alphabeta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pTalpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse epithelial cell line PAM212
NCBI Gene ID #:
12520
NCBI Official Name:
CD81 antigen
NCBI Official Symbol:
Cd81
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P35762
Research Area:
Immunology
SPECIFICITY:
CD81
Swissprot #:
P35762
User NOte:
Optimal dilutions for each application to be determined by the researcher.