CD86 Antibody [2D10] (FITC)
| Code | Size | Price |
|---|
| PSI-99-094-0.5mg | 0.5mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: [2D10]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Immunocytochemistry (ICC)
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
B7-2, B70, Ly-58
Application Note:
CD86 Antibody [2D10] for use in flow cytometry and immunohistochemistry assays.
Background:
CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4). It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse B cell lymphoma cell line 5C2
NCBI Gene ID #:
12524
NCBI Official Name:
CD86 antigen
NCBI Official Symbol:
Cd86
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P42082
Research Area:
Innate Immunity
SPECIFICITY:
CD86
Swissprot #:
P42082
User NOte:
Optimal dilutions for each application to be determined by the researcher.