CD86 Antibody [GL1] (Biotin)
| Code | Size | Price |
|---|
| PSI-98-854-0.5mg | 0.5mg | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [GL1]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
B7-2, B70, Ly-58
Application Note:
CD86 Antibody [GL1] for use in flow cytometry, immunohistochemistry, and immunoprecipitation assays.
Background:
CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80 (B7-1), is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152 (CTLA-4). Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. The monoclonal antibody GL1 blocks mixed lymphocyte reactions and stimulation of T cells by antigen-presenting cells.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
Biotin
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
LPS-activated CBA/Ca mouse spleen B cells
NCBI Gene ID #:
12524
NCBI Official Name:
CD86 antigen
NCBI Official Symbol:
Cd86
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P42082
Research Area:
Innate Immunity
SPECIFICITY:
CD86
Swissprot #:
P42082
User NOte:
Optimal dilutions for each application to be determined by the researcher.