CD95 Antibody [DX2] (PE)
| Code | Size | Price |
|---|
| PSI-99-579-100tests | 100tests | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [DX2]
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
APO-1, Fas, TNFRSF6
Application Note:
CD95 Antibody [DX2] for use in flow cytometry assays.
Background:
CD95, also known as Fas and APO-1, is a 45 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts, and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells indicating that these monoclonal antibodies recognize a functional epitope of CD95.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
Lot specific
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human CD95 transfected L cells
NCBI Gene ID #:
355
NCBI Official Name:
Tumor necrosis factor receptor superfamily member 6
NCBI Official Symbol:
FAS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P25445
Research Area:
Cancer,Cell Cycle,Immunology,Signal Transduction
SPECIFICITY:
CD95
Swissprot #:
P25445
User NOte:
Optimal dilutions for each application to be determined by the researcher.