MCAM Antibody [C264] (PE)

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ProSci
Product Code: PSI-99-305
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-99-305-0.1mg0.1mg£560.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: [C264]
Regulatory Status: RUO
Target Species:
  • Chicken (Gallus)
  • Turkey
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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Chicken thymocytes were stained with Mouse Anti-Chicken MCAM-PE (Cat. No. 99-305).
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Chicken thymocytes were stained with Mouse Anti-Chicken MCAM-PE (Cat. No. 99-305).

Documents

Further Information

Additional Names:
CD146, HEMCAM, melanoma cell adhesion molecule
Application Note:
MCAM Antibody [C264] for use in flow cytometry assays.
Background:
Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm?s kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos
NCBI Gene ID #:
448832
NCBI Official Name:
melanoma cell adhesion molecule
NCBI Official Symbol:
MCAM
NCBI Organism:
Gallus gallus
Physical State:
Liquid
Research Area:
Cancer,Immunology,Signal Transduction
SPECIFICITY:
MCAM
User NOte:
Optimal dilutions for each application to be determined by the researcher.