CLEC1 Antibody
| Code | Size | Price |
|---|
| PSI-33-024-100ug | 100ug | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Application Note:
Western blot: 2-5 ug/ml
Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
Background:
CLEC1 is a C-type lectin receptor and part of the ?Dectin-1 cluster? subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.
NCBI Gene ID #:
51267
NCBI Official Name:
C-type lectin domain family 1 member A
NCBI Official Symbol:
CLEC1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A purified antibody
Research Area:
Immunology, Signal Transduction
Swissprot #:
Q8NC01
User NOte:
Optimal dilutions for each application to be determined by the researcher