DC-SIGN Antibody [C209/1781]
| Code | Size | Price |
|---|
| PSI-33-797-100ug | 100ug | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: C209/1781
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
DC-SIGN Antibody: CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, CD209 antigen, C-type lectin domain family 4 member L
Application Note:
IF: 1-2 ug/ml
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
IHC (FFPE): 0.5-1 ug/ml for 30 min at RT
Titering of the DC-SIGN antibody may be required for optimal performance.
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
IHC (FFPE): 0.5-1 ug/ml for 30 min at RT
Titering of the DC-SIGN antibody may be required for optimal performance.
Background:
DC-SIGN / CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A human partial recombinant protein was used as the immunogen for the DC-SIGN antibody.
NCBI Gene ID #:
30835
NCBI Official Name:
CD209 molecule
NCBI Official Symbol:
CD209
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Infectious Disease
Swissprot #:
Q9NNX6
User NOte:
Optimal dilutions for each application to be determined by the researcher