EDG1 Antibody

Contact us
ProSci
Product Code: PSI-33-006
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-006-100ug100ug£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

1 / 1
Western blot testing of human samples with EDG1 antibody at 4ug/ml.
❮❯

Western blot testing of human samples with EDG1 antibody at 4ug/ml.

Documents

Further Information

Additional Names:
S1P1 Antibody: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, EDG1, Sphingosine 1-phosphate receptor 1, Endothelial differentiation G-protein coupled receptor 1, S1P receptor 1
Application Note:
Western blot: 4-6 ug/ml

Provided assay concentrations are suggestions only, EDG1 antibody titration may be required for optimal results.
Background:
EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.
NCBI Gene ID #:
1901
NCBI Official Name:
sphingosine-1-phosphate receptor 1
NCBI Official Symbol:
S1PR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Immunology
Swissprot #:
P21453
User NOte:
Optimal dilutions for each application to be determined by the researcher