FGF-23 Antibody [FGF23/638]

ProSci
Product Code: PSI-33-227
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-227-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: FGF23/638
Regulatory Status: RUO
Target Species: Human
Application: Functional Study
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Further Information

Additional Names:
Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor
Application Note:
ELISA: order BSA-free format for coating

Functional testing: order BSA/azide-free format

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FGF-23 antibody to be titered up or down for optimal performance.
Background:
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi), FGF5, FGF6, FGF7 (KGF), FGF8 (AIGF), FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant human FGF-23 protein was used as the immunogen for this antibody.
NCBI Gene ID #:
8074
NCBI Official Name:
fibroblast growth factor 23
NCBI Official Symbol:
FGF23
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G purified FGF-23 antibody
Research Area:
Obesity
Swissprot #:
Q9GZV9
User NOte:
Optimal dilutions for each application to be determined by the researcher