GPR77 Antibody

ProSci
Product Code: PSI-33-046
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-046-100ug100ug£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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Western blot testing of human samples using GPR77 antibody at 1ug/ml.

Western blot testing of human samples using GPR77 antibody at 1ug/ml.

Further Information

Application Note:
Western blot: 1-3 ug/ml

Provided assay concentrations are suggestions only, GPR77 antibody titration may be required for optimal results.
Background:
G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the N-terminal region of human GPR77 was used as the immunogen for this antibody.
NCBI Gene ID #:
445269
NCBI Official Name:
complement component 5a receptor 2
NCBI Official Symbol:
C5ar2
NCBI Organism:
Rattus norvegicus (Norway rat)
Physical State:
Liquid
Purification:
Protein A Affinity Chromatography
Research Area:
Signal Transduction
Swissprot #:
Q695P6
User NOte:
Optimal dilutions for each application to be determined by the researcher