GSK-3a Antibody [SBGSK3a2]
| Code | Size | Price |
|---|
| PSI-99-742-0.1mg | 0.1mg | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [SBGSK3a2]
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Glycogen synthase kinase-3
Application Note:
GSK-3a Antibody [SBGSK3a2] for use in western blotting assays.
Background:
Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3alpha and GSK-3beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
2931
NCBI Official Name:
Glycogen synthase kinase-3 alpha
NCBI Official Symbol:
GSK3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P49840
Research Area:
Cell Cycle,Neuroscience,Signal Transduction
SPECIFICITY:
GSK-3alpha
Swissprot #:
P49840
User NOte:
Optimal dilutions for each application to be determined by the researcher.