CD8beta Antibody [EP42] (PE)
| Code | Size | Price |
|---|
| PSI-99-249-0.1mg | 0.1mg | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [EP42]
Regulatory Status: RUO
Target Species: Chicken (Gallus)
Applications:
- Blocking
- Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Application Note:
CD8beta Antibody [EP42] for use in flow cytometry assays.
Background:
In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8alpha- and CD8beta-chains, a relatively large proportion of the CD8+ TCR-gammadelta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR-gammadelta CD8alphabeta cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody EP42 recognizes the CD8beta chain.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Chicken splenocytes
NCBI Gene ID #:
396175
NCBI Official Name:
CD8b molecule
NCBI Official Symbol:
CD8B
NCBI Organism:
Gallus gallus
Physical State:
Liquid
Research Area:
Cancer,Immunology
SPECIFICITY:
CD8beta
User NOte:
Optimal dilutions for each application to be determined by the researcher.