IL-21 Antibody [SB134f]

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ProSci
Product Code: PSI-99-804
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-99-804-0.5mg0.5mg£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [SB134f]
Regulatory Status: RUO
Target Species: Human
Applications:
  • Electron microscopy
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

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Further Information

Additional Names:
Interleukin-21, Za11
Application Note:
IL-21 Antibody [SB134f] for use in ELISA assays.
Background:
Interleukin-21 (IL-21) is a four helical bundle type I cytokine. The mature form of human IL-21 is a 131 amino acid protein. IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells, and augmentation of antitumor activity of CD8+ T cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
E. coli-expressed human IL-21
NCBI Gene ID #:
59067
NCBI Official Name:
interleukin 21
NCBI Official Symbol:
IL21
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q9HBE4
Research Area:
Immunology,Chemokines & Cytokines
SPECIFICITY:
IL-21
Swissprot #:
Q9HBE4
User NOte:
Optimal dilutions for each application to be determined by the researcher.