Cytokeratin 19 Antibody [SB39g] (FITC)

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ProSci
Product Code: PSI-99-633
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-99-633-0.1mg0.1mg£597.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [SB39g]
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 19-FITC (Cat. No. 99-633).
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Human pancreatic carcinoma cell line MIA PaCa-2 was stained with Mouse Anti-Cytokeratin 19-FITC (Cat. No. 99-633).

Documents

Further Information

Additional Names:
CK 19, keratin 19
Application Note:
Cytokeratin 19 Antibody [SB39g] for use in flow cytometry, immunocytochemistry, and western blotting assays.
Background:
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 19 is the smallest human keratin. It is found in many simple and some non-keratinizing stratified squamous epithelia and is often co-expressed with keratin 7. Cytokeratin 19 has been implicated as a marker for stem cells in some tissues such as hair follicles in the skin. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. The degree of cytokeratin 19 positivity in breast cancer distinguishes malignant from benign tumors. Cytokeratin 19 is also associated with malignant transformation in esophageal and pancreatic cancers.
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant C-terminal cytokeratin 19
NCBI Gene ID #:
3880
NCBI Official Name:
Keratin, type I cytoskeletal 19
NCBI Official Symbol:
KRT19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P08727
Research Area:
Signal Transduction
SPECIFICITY:
Cytokeratin 19
Swissprot #:
P08727
User NOte:
Optimal dilutions for each application to be determined by the researcher.