Cytokeratin 18 Antibody [SB38b]
| Code | Size | Price |
|---|
| PSI-99-628-0.1mg | 0.1mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: [SB38b]
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
CK 18, keratin 18
Application Note:
Cytokeratin 18 Antibody [SB38b] for use in flow cytometry, immunocytochemistry, ELISA, western blotting assays.
Background:
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant N-terminal cytokeratin 18
NCBI Gene ID #:
3875
NCBI Official Name:
Keratin, type I cytoskeletal 18
NCBI Official Symbol:
KRT18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P05783
Research Area:
Signal Transduction
SPECIFICITY:
Cytokeratin 18
Swissprot #:
P05783
User NOte:
Optimal dilutions for each application to be determined by the researcher.