Ly-6A/E Antibody [D7] (PE)
| Code | Size | Price |
|---|
| PSI-98-877-0.1mg | 0.1mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [D7]
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Sca-1
Application Note:
Ly-6A/E Antibody [D7] for use in flow cytometry assays.
Background:
Ly-6A/E, also known as Sca-1, is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. In the periphery, Ly-6A/E exhibits a pattern of expression which is based on differences between the two allotypes. Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Ly-6A/E+ resting peripheral lymphocytes whereas Ly-6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Ly-6A/E+ lymphocytes. The expression of Ly-6A/E is dramatically upregulated in all strains upon cellular activation. Studies with the monoclonal antibody D7 suggest that Ly-6A/E may be involved in B and T lymphocyte responses and it appears that the antigen may be required for T-cell receptor-mediated T-cell activation.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IL-2 dependent mouse (C57BL/6) cytotoxic T cell line CTL-L
NCBI Gene ID #:
110454
NCBI Official Name:
lymphocyte antigen 6 complex, locus A
NCBI Official Symbol:
Ly6a
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P05533
Research Area:
Innate Immunity,Stem Cell
SPECIFICITY:
Ly-6A/E
Swissprot #:
P05533
User NOte:
Optimal dilutions for each application to be determined by the researcher.