MUC2 Antibody [MUCN2-1]

ProSci
Product Code: PSI-33-962
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-962-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: MUCN2-1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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Formalin-fixed, paraffin-embedded human colon carcinoma stained with MUC2 antibody (MLP/842).

Formalin-fixed, paraffin-embedded human colon carcinoma stained with MUC2 antibody (MLP/842).

Further Information

Additional Names:
MUC2, Intestinal mucin-2, Mucin-like protein, MUC-2, Mucin 2, intestinal/tracheal, Mucin 2, Mucin-2, MLP, SMUC
Application Note:
Immunofluorescence: 1-2 ug/ml

Immunohistochemistry (FFPE): 1-2 ug/ml for 30 min at RT (1)

Prediluted format : incubate for 30 min at RT (2)

Titering of the MUC2 antibody may be required for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Background:
Mucin 2 coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. [UniProt]
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human protein was used as the immunogen for the MUC2 antibody.
NCBI Gene ID #:
4583
NCBI Official Name:
mucin 2, oligomeric mucus/gel-forming
NCBI Official Symbol:
MUC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Cancer, Signal Transduction
SPECIFICITY:
Does not react with rat
Swissprot #:
Q02817
User NOte:
Optimal dilutions for each application to be determined by the researcher