NQO1 Antibody
Code | Size | Price |
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PSI-33-029-100ug | 100ug | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
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Further Information
Additional Names:
NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
Application Note:
Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
Background:
NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC or ?non-small cell lung cancer,? suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
NCBI Gene ID #:
1728
NCBI Official Name:
NAD(P)H dehydrogenase, quinone 1
NCBI Official Symbol:
NQO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Obesity,Signal Transduction
Swissprot #:
P15559
User NOte:
Optimal dilutions for each application to be determined by the researcher