NKIRAS1 Antibody [NRAS285]

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ProSci
Product Code: PSI-33-038
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-038-100ug100ug£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: NRAS285
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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Western blot testing of human samples with NKIRAS1 antibody at 6ug/ml.
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Western blot testing of human samples with NKIRAS1 antibody at 6ug/ml.

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Further Information

Additional Names:
KappaB ras Antibody: KBRAS1, kappaB-Ras1, KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1
Application Note:
Western blot: 5-10 ug/ml

Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.
Background:
NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.

NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.

Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
NCBI Gene ID #:
28512
NCBI Official Name:
NFKB inhibitor interacting Ras-like 1
NCBI Official Symbol:
NKIRAS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G purified antibody
Research Area:
Signal Transduction
Swissprot #:
Q9NYS0
User NOte:
Optimal dilutions for each application to be determined by the researcher