Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]

PD-1 Antibody: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PD1, Programmed cell death protein 1, Protein PD-1, PDCD1, PDCD-1

Immunohistochemistry (FFPE): 1-2 ug/ml for 30 min at RT



Prediluted IHC only format: incubate for 30 min at RT (1)

Immunofluorescence: 1-2 ug/ml

Flow Cytometry: 0.5-1ug/10e6 cells in 0.1ml

Titering of the recombinant PD1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

0.2 mg/mL

Unconjugated

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

5133

programmed cell death 1

PDCD1

mus musculus

Liquid

Protein A affinity chromatography

Immunology,Cancer,Cell Cycle

Q15116

Optimal dilutions for each application to be determined by the researcher