Semaphorin-4D Antibody [133-1C6]
| Code | Size | Price |
|---|
| PSI-33-325-100ug | 100ug | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgM, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 133-1C6
Regulatory Status: RUO
Target Species:
- Baboon
- Human
Application: Immunofluorescence (IF)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Application Note:
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 0.5-1 ug/ml
Optimal dilution of the Semaphorin-4D antibody to be determined by the researcher.
Immunofluorescence: 0.5-1 ug/ml
Optimal dilution of the Semaphorin-4D antibody to be determined by the researcher.
Background:
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
PHA stimulated human peripheral blood lymphocytes were used as the immunogen for the Semaphorin-4D antibody.
NCBI Gene ID #:
10507
NCBI Official Name:
semaphorin 4D
NCBI Official Symbol:
SEMA4D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
PEG precipitation
Research Area:
Immunology, Neuroscience
SPECIFICITY:
Does not react with Horse
Swissprot #:
Q92854
User NOte:
Optimal dilutions for each application to be determined by the researcher