Semaphorin-4D Antibody [SEMA4D/933]

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ProSci
Product Code: PSI-33-327
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-327-100ug100ug£765.00
Quantity:
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Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SEMA4D/933
Regulatory Status: RUO
Target Species:
  • Human
  • Non-Human Primates
Application: Immunofluorescence (IF)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Documents

Further Information

Application Note:
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml

Immunofluorescence: 0.5-1 ug/ml

Optimal dilution of the Semaphorin-4D antibody should be determined by the researcher.
Background:
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Human recombinant protein was used as the immunogen for the Semaphorin-4D antibody.
NCBI Gene ID #:
10507
NCBI Official Name:
semaphorin 4D
NCBI Official Symbol:
SEMA4D
NCBI Organism:
homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Immunology, Neuroscience
Swissprot #:
Q92854
User NOte:
Optimal dilutions for each application to be determined by the researcher