Desmoglein 3 Antibody [5H10]

ProSci
Product Code: PSI-33-628
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-628-100ug100ug£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 5H10
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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SDS-PAGE Analysis of Purified, BSA-Free Desmoglein 3 Antibody (clone 5H10). Confirmation of Integrity and Purity of the Antibody.

SDS-PAGE Analysis of Purified, BSA-Free Desmoglein 3 Antibody (clone 5H10). Confirmation of Integrity and Purity of the Antibody.

Further Information

Application Note:
WB: 0.5-1 ug/ml

Flow Cytometry: 0.5-1 ug/million cells in 0.1ml

Immunofluorescence: 1-2 ug/ml

Immunoprecipitation: suitable

Optimal dilution of the Desmoglein 3 antibody should be determined by the researcher.
Background:
Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant human protein corresponding to the extracellular portion of DSG3 was used as the immunogen for the Desmoglein 3 antibody.
NCBI Gene ID #:
1830
NCBI Official Name:
desmoglein 3
NCBI Official Symbol:
DSG3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Signal Transduction
Swissprot #:
P32926
User NOte:
Optimal dilutions for each application to be determined by the researcher