hCG Receptor / LH Receptor Antibody [LHCGR/1415]
| Code | Size | Price |
|---|
| PSI-33-714-100ug | 100ug | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: LHCGR/1415
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
LHCGR, luteinizing hormone/choriogonadotropin receptor, LCGR, LGR2, LHR, hLHR, luteinizing hormone receptor, lutropin/choriogonadotropin receptor, LH receptor, CG receptor, LHRHR
Application Note:
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
IF: 1-2 ug/ml
WB: 0.5-1 ug/ml
Optimal dilution of the hCG Receptor antibody should be determined by the researcher.
IF: 1-2 ug/ml
WB: 0.5-1 ug/ml
Optimal dilution of the hCG Receptor antibody should be determined by the researcher.
Background:
Recognizes a protein of 78-85kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.
NCBI Gene ID #:
3973
NCBI Official Name:
luteinizing hormone/choriogonadotropin receptor
NCBI Official Symbol:
LHCGR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Cancer
Swissprot #:
P22888
User NOte:
Optimal dilutions for each application to be determined by the researcher