Smac/DIABLO Antibody [2D12]
| Code | Size | Price |
|---|
| PSI-99-765-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: [2D12]
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Frozen Section (IHC-F)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
SMAC3, DIABLO-S , FLJ10537, FLJ25049, 0610041G12Rik
Application Note:
Smac/DIABLO Antibody [2D12] for use in ELISA and western blotting assays.
Background:
Smac/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. Smac/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor of apoptosis protein (IAP) family, a major group of apoptosis regulators that have been shown to directly block caspase activity thereby blocking apoptosis.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant Smac/DIABLO
NCBI Gene ID #:
56616
NCBI Official Name:
diablo, IAP-binding mitochondrial protein
NCBI Official Symbol:
DIABLO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q502X2
Research Area:
Transcription,Cancer
SPECIFICITY:
Smac/DIABLO
Swissprot #:
Q502X2
User NOte:
Optimal dilutions for each application to be determined by the researcher.