SPIB Antibody

ProSci
Product Code: PSI-33-005
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-33-005-100ug100ug£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

1 / 1
Western blot testing of human samples with SPIB antibody at 4ug/ml.

Western blot testing of human samples with SPIB antibody at 4ug/ml.

Further Information

Additional Names:
Spi-B transcription factor, SPI-B
Application Note:
Western blot: 4-8 ug/ml

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Background:
SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.
NCBI Gene ID #:
6689
NCBI Official Name:
Spi-B transcription factor (Spi-1/PU.1 related)
NCBI Official Symbol:
SPIB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein A affinity chromatography
Research Area:
Stem Cell,Immunology
Swissprot #:
Q01892
User NOte:
Optimal dilutions for each application to be determined by the researcher