TCR beta Antibody [H57-597]

ProSci
Product Code: PSI-98-898
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-98-898-0.5mg0.5mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: [H57-597]
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Blocking
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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Further Information

Application Note:
TCR beta Antibody [H57-597] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, stimulaton, separation, and depletion assays.
Background:
The alphabeta TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with gammadelta TCR-bearing cells. Plate-bound or soluble H57-597 activates alphabeta TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete alphabeta TCR-bearing cells to near completion and prevent graft rejection.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TCR affinity purified from mouse T-cell hybridoma DO-11.10
NCBI Gene ID #:
21577
NCBI Official Name:
T cell receptor beta chain
NCBI Official Symbol:
Tcrb
NCBI Organism:
Mus musculus
Physical State:
Liquid
Research Area:
Immunology
SPECIFICITY:
TCRbeta
User NOte:
Optimal dilutions for each application to be determined by the researcher.