CD45.2 Antibody [104] (Biotin)

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ProSci
Product Code: PSI-98-926
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-98-926-0.5mg0.5mg£560.00
Quantity:
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Overview

Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [104]
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Blocking
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C

Images

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BALB/c mouse bone marrow cells were stained with Mouse Anti-Mouse CD45.2-BIOT (Cat. No. 98-926) followed by Streptavidin-FITC .
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BALB/c mouse bone marrow cells were stained with Mouse Anti-Mouse CD45.2-BIOT (Cat. No. 98-926) followed by Streptavidin-FITC .

Documents

Further Information

Additional Names:
Ly-5.2, LCA, SJL, T200
Application Note:
CD45.2 Antibody [104] for use in flow cytometry and immunohistochemistry assays.
Background:
The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosporylate the Src family of protein kinases. This activity is known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685 and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody 104 recognizes CD45 (leukocyte common antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129).
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
Biotin
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
B10.S mouse thymocytes and splenocytes
NCBI Gene ID #:
19264
NCBI Official Name:
protein tyrosine phosphatase, receptor type, C
NCBI Official Symbol:
Ptprc
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P06800
Research Area:
Immunology
SPECIFICITY:
CD45.2
Swissprot #:
P06800
User NOte:
Optimal dilutions for each application to be determined by the researcher.