Fibrillin Antibody [11C1.3] (Biotin)
| Code | Size | Price |
|---|
| PSI-98-521-0.2mg | 0.2mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: [11C1.3]
Regulatory Status: RUO
Target Species:
- Bovine (Cattle)
- Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
FBN1
Application Note:
Fibrillin Antibody [11C1.3] for use in immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.
Background:
The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear. There is an aberrant expression of fibrillin in Marfan syndrome. The epitope for the monoclonal antibody 11C1.3 has been found to be within exons 18-20 (a.a. 723-909).
Buffer:
Supplied in PBS/NaN3
Concentration:
0.2 mg/mL
Conjugate:
Biotin
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Microfibrils from the zonular apparatus of bovine eye
NCBI Gene ID #:
2200
NCBI Official Name:
fibrillin 1
NCBI Official Symbol:
FBN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q75N89
Research Area:
Cancer,Signal Transduction
SPECIFICITY:
Fibrillin
Swissprot #:
Q75N89
User NOte:
Optimal dilutions for each application to be determined by the researcher.