FTL1 Antibody [FTL/1389]

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ProSci
Product Code: PSI-33-713
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-33-713-100ug100ug£765.00
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: FTL/1389
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.

Images

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IHC testing of FFPE human pancreas with Ferritin Light Chain antibody (clone FTL/1389). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
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IHC testing of FFPE human pancreas with Ferritin Light Chain antibody (clone FTL/1389). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.

Documents

Further Information

Additional Names:
FTL, MGC71996, LFTD, NBIA3
Application Note:
Flow Cytometry: 0.1-0.2ug/10^6 cells

IF: 0.1-0.2 ug/ml

IHC (FFPE): 0.1-0.2 ug/ml for 30 min at RT

Optimal dilution of the Ferritin Light Chain antibody should be determined by the researcher.
Background:
The FTL gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. This gene has multiple pseudogenes.

Although ferritin light chain has no ferroxidase activity, the light chain may be responsible for the electron transfer across the ferritin protein cage. [Wiki]

Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.2 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.
NCBI Gene ID #:
2512
NCBI Official Name:
ferritin, light polypeptide
NCBI Official Symbol:
FTL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G affinity chromatography
Research Area:
Obesity, Neuroscience, Signal Transduction
Swissprot #:
P02792
User NOte:
Optimal dilutions for each application to be determined by the researcher