LPAM-1 Antibody [DATK32]
| Code | Size | Price |
|---|
| PSI-99-009-0.5mg | 0.5mg | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: [DATK32]
Regulatory Status: RUO
Target Species: Mouse
Application: Immunocytochemistry (ICC)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Integrin alpha4beta7, lymphocyte Peyer's patch adhesion molecule
Application Note:
LPAM-1 Antibody [DATK32] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.
Background:
The lymphocyte Peyer?s patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer?s patches and intestinal lamina propria. The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer.
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
AKR/Cum mouse T lymphoma cell line TK-1
NCBI Gene ID #:
16401/16421
NCBI Official Name:
integrin alpha 4; integrin beta 7
NCBI Official Symbol:
Itga4; Itgb7
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q00651; P26011
Research Area:
Immunology,Signal Transduction,Stem Cell
SPECIFICITY:
LPAM-1
Swissprot #:
Q00651; P26011
User NOte:
Optimal dilutions for each application to be determined by the researcher.