TLR9 Antibody [TR9541]
| Code | Size | Price |
|---|
| PSI-33-002-100ug | 100ug | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: TR9541
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Documents
Further Information
Additional Names:
TLR9 Antibody: CD289, Toll-like receptor 9
Application Note:
Western blot: 2-4 ug/ml
Flow Cytometry: 1ug/10e6 cells
Immunohistochemistry (Paraffin): 3-5 ug/ml (1)
1. For optimal TLR9 staining, formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Flow Cytometry: 1ug/10e6 cells
Immunohistochemistry (Paraffin): 3-5 ug/ml (1)
1. For optimal TLR9 staining, formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Background:
The mammalian immune system is composed of two components: innate immunity and adaptive immunity. Toll-like receptors (TLRs) are an essential part of the innate immune system. Through recognition of pathogen-associated molecular patterns (PAMPs), TLRs mount an immune defense against pathogens. There are 10 mammalian TLRs (TLR1-10). Unmethylated CpG sequences in bacterial genomes and viral DNA molecules activates TLR9, leading to the inflammatory response.
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A recombinant protein fragment from the N-terminal portion of human TLR9 was used as the immunogen for this antibody.
NCBI Gene ID #:
54106
NCBI Official Name:
toll-like receptor 9
NCBI Official Symbol:
TLR9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Protein G Affinity Chromatography
Research Area:
Signal Transduction,Innate Immunity
Swissprot #:
Q9NR96
User NOte:
Optimal dilutions for each application to be determined by the researcher