Ly-49C/F/H/I Antibody [14B11] (FITC)
| Code | Size | Price |
|---|
| PSI-98-935-0.5mg | 0.5mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: [14B11]
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Blocking
- Immunocytochemistry (ICC)
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
blue ice
Storage:
Store vial at 2-8˚C
Documents
Further Information
Additional Names:
Ly-49
Application Note:
Ly-49C/F/H/I Antibody [14B11] for use in flow cytometry assays.
Background:
The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H, and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains ~90% of NK1.1+CD3- splenocytes and ~6% of CD8+ spleen cells from C57BL/6 mice. The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).
Buffer:
Supplied in PBS/NaN3
Concentration:
0.5 mg/mL
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IL-2 activated natural killed (A-LAK) cells from C57BL/6 mice
NCBI Gene ID #:
16634/16637/16639/16640
NCBI Official Name:
killer cell lectin-like receptor, subfamily A, member 3
NCBI Official Symbol:
Klra3
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q64329
Research Area:
Immunology
SPECIFICITY:
Ly-49C/F/H/I
Swissprot #:
Q64329
User NOte:
Optimal dilutions for each application to be determined by the researcher.